HTLV1 Target gene Detail Information

> ERBB4 Gene Search Result


Gene Information
Gene Name ERBB4
Gene ID 2066
Gene Full Name erb-b2 receptor tyrosine kinase 4
Gene Alias HER4; ALS19; p180erbB4
Transcripts ENSG00000178568
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Gene Function Suppressor gene & Oncogene
Uniport_ID Q15303
HGNC ID HGNC:3432
VEGA ID OTTHUMG00000133012
OMIM ID 600543
String ID 9606.ENSP00000342235
Drugbank ID BE0004772
Drug (Cytoscape Annotation) Lapatinib Ditosylate;Gefitinib;Dasatinib;AfatinibDimaleate;Bosutinib;Erlotinib Hydrochloride;Vandetanib
PharmGKB ID PA27847
FDA Approved Drug Dacomitinib
Target gene [ERBB4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6011769 chr2 24 1 25 View
6023960 chr2 4 4 View
6025386 chr2 3 3 View
6029504 chr2 1 1 View
6033518 chr2 0 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).