HPV Target gene Detail Information

> ERBB2 Gene Search Result

Gene Information

Gene Name	ERBB2
Gene ID	2064
Gene Full Name	erb-b2 receptor tyrosine kinase 2
Gene Alias	NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu
Transcripts	ENSG00000141736
Virus	HPV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	P04626
HGNC ID	HGNC:3430
VEGA ID	OTTHUMG00000179300
OMIM ID	164870
String ID	9606.ENSP00000269571
Drugbank ID	BE0000511
PharmGKB ID	PA27844
FDA Approved Drug	Abemaciclib;Ado-Trastuzumab Emtansine;Alpelisib;Eribulin;Everolimus;Fam-Trastuzumab Deruxtecan-nxki;Fulvestrant;Ixabepilone;Lapatinib;Margetuximab-cmkb;Neratinib;Olaparib;Palbociclib;Pertuzumab;Ribociclib;Talazoparib;Tipiracil;Trifluridine;Trastuzumab;Tucatinib

Target gene [ERBB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5000185	chr17	131	426	185	742	View
5000546	chr17	114	25	1	140	View
5000589	chr17	115	11		126	View
5000590	chr17	115	11		126	View
5000591	chr17	114	12		126	View
5000773	chr17	80	7		87	View
5002783	chr17	7	1		8	View
5300273	chr17	238	214	55	507	View
5300274	chr17	243	168	49	460	View
5300275	chr17	85	4		89	View
5300276	chr17	666	4	3	673	View
5300277	chr17	767	14	21	802	View
5300278	chr17	41	10	19	70	View
5300279	chr17	79	3		82	View
5300280	chr17	4			4	View
5300281	chr17	4	1		5	View
5402648	chr17	1	2		3	View
5402649	chr17	31	6		37	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).