HTLV1 Target gene Detail Information

> EPX Gene Search Result

Gene Information

Gene Name	EPX
Gene ID	8288
Gene Full Name	eosinophil peroxidase
Gene Alias	EPO; EPP; EPXD; EPX-PEN
Transcripts	ENSG00000121053
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P11678
HGNC ID	HGNC:3423
VEGA ID	OTTHUMG00000178802
OMIM ID	131399
String ID	9606.ENSP00000225371
Drugbank ID	BE0003555
PharmGKB ID	PA27841

Target gene [EPX] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002196	chr17	23	236	12	271	View
6002197	chr17	23	236	12	271	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of EPX expression and immune infiltrating cell level correlation result in HTLV1+ samples
EPX expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of EPX expression and immune infiltrating cell level correlation result in HTLV1+ samples
EPX expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of EPX expression and immune infiltrating cell level correlation result in HTLV1+ samples
EPX expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).