HIV Target gene Detail Information

> EPHA1 Gene Search Result

Gene Information

Gene Name	EPHA1
Gene ID	2041
Gene Full Name	EPH receptor A1
Gene Alias	EPH; EPHT; EPHT1
Transcripts	ENSG00000284816
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	P21709
HGNC ID	HGNC:3385
VEGA ID	OTTHUMG00000155894
OMIM ID	179610
String ID	9606.ENSP00000275815
Drugbank ID	BE0009390
PharmGKB ID	PA27817

Target gene [EPHA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000206	chr7	399	221	123	743	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EPHA1 expression and immune infiltrating cell level correlation result in HIV+ samples
EPHA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).