HIV Target gene Detail Information

> EPCAM Gene Search Result

Gene Information

Gene Name	EPCAM
Gene ID	4072
Gene Full Name	epithelial cell adhesion molecule
Gene Alias	ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1
Transcripts	ENSG00000119888
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	P16422
HGNC ID	HGNC:11529
VEGA ID	OTTHUMG00000128853
OMIM ID	185535
String ID	9606.ENSP00000263735
Drugbank ID	BE0002446
PharmGKB ID	PA35493

Target gene [EPCAM] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010308	chr2	9			9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EPCAM expression and immune infiltrating cell level correlation result in HIV+ samples
EPCAM expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).