HIV Target gene Detail Information

> EPC1 Gene Search Result

Gene Information

Gene Name	EPC1
Gene ID	80314
Gene Full Name	enhancer of polycomb homolog 1
Gene Alias	Epl1
Transcripts	ENSG00000120616
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9H2F5
HGNC ID	HGNC:19876
VEGA ID	OTTHUMG00000017925
OMIM ID	610999
String ID	9606.ENSP00000263062
PharmGKB ID	PA134981141

Target gene [EPC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004097	chr10	47	1	1	49	View
4004152	chr10	15		33	48	View
4004512	chr10	40	3		43	View
4008387	chr10	14	1		15	View
4012795	chr10	1	1	2	4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EPC1 expression and immune infiltrating cell level correlation result in HIV+ samples
EPC1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EPC1 expression and immune infiltrating cell level correlation result in HIV+ samples
EPC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).