HBV Target gene Detail Information

> EPB41L3 Gene Search Result


Gene Information
Gene Name EPB41L3
Gene ID 23136
Gene Full Name erythrocyte membrane protein band 4.1 like 3
Gene Alias 4.1B; DAL1; DAL-1
Transcripts ENSG00000082397
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID Q9Y2J2
HGNC ID HGNC:3380
VEGA ID OTTHUMG00000131562
OMIM ID 605331
String ID 9606.ENSP00000343158
PharmGKB ID PA27813
Target gene [EPB41L3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006059 chr18 42 2 44 View
1404664 chr18 75 91 138 304 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of EPB41L3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
EPB41L3 expression: Low -> High
Lollipop of EPB41L3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of EPB41L3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EPB41L3 expression and immune infiltrating cell level correlation result in HBV+ samples
EPB41L3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).