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HBV Target gene Detail Information

> EP400 Gene Search Result


Gene Information
Gene Name EP400
Gene ID 57634
Gene Full Name E1A binding protein p400
Gene Alias P400; CAGH32; TNRC12
Transcripts ENSG00000183495
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q96L91
HGNC ID HGNC:11958
VEGA ID OTTHUMG00000187346
OMIM ID 606265
String ID 9606.ENSP00000374213
PharmGKB ID PA27808
Target gene [EP400] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000217 chr12 3593 234 110 3937 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of EP400 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
EP400 expression: Low -> High
Lollipop of EP400 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of EP400 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EP400 expression and immune infiltrating cell level correlation result in HBV+ samples
EP400 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).