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HPV Target gene Detail Information

> ENTPD5 Gene Search Result


Gene Information
Gene Name ENTPD5
Gene ID 957
Gene Full Name ectonucleoside triphosphate diphosphohydrolase 5
Gene Alias PCPH; CD39L4; NTPDase-5
Transcripts ENSG00000187097
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Gene Function Oncogene
Uniport_ID O75356
HGNC ID HGNC:3367
VEGA ID OTTHUMG00000171201
OMIM ID 603162
String ID 9606.ENSP00000335246
Drugbank ID BE0010158
PharmGKB ID PA27802
Target gene [ENTPD5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5400154 chr14 5 5 View
5401312 chr14 5 5 View
5401375 chr14 5 5 View
5401586 chr14 5 5 View
5401820 chr14 5 5 View
5402314 chr14 5 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of ENTPD5 expression and immune infiltrating cell level correlation result in HPV+ samples
ENTPD5 expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of ENTPD5 expression and immune infiltrating cell level correlation result in HPV+ samples
ENTPD5 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of ENTPD5 expression and immune infiltrating cell level correlation result in HPV+ samples
ENTPD5 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).