HPV Target gene Detail Information

> ENSA Gene Search Result


Gene Information
Gene Name ENSA
Gene ID 2029
Gene Full Name endosulfine alpha
Gene Alias ARPP-19e
Transcripts ENSG00000143420
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoli;Nucleoplasm;Cytosol;Microtubules;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O43768
HGNC ID HGNC:3360
VEGA ID OTTHUMG00000035004
OMIM ID 603061
String ID 9606.ENSP00000341743
PharmGKB ID PA27796
Target gene [ENSA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5300270 chr1 635 11 646 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of ENSA expression and immune infiltrating cell level correlation result in HPV+ samples
ENSA expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of ENSA expression and immune infiltrating cell level correlation result in HPV+ samples
ENSA expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of ENSA expression and immune infiltrating cell level correlation result in HPV+ samples
ENSA expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).