HBV Target gene Detail Information

> ENPP1 Gene Search Result

Gene Information

Gene Name	ENPP1
Gene ID	5167
Gene Full Name	ectonucleotide pyrophosphatase/phosphodiesterase 1
Gene Alias	M6S1; NPP1; NPPS; PC-1; PCA1; ARHR2; COLED; PDNP1
Transcripts	ENSG00000197594
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID	P22413
HGNC ID	HGNC:3356
VEGA ID	OTTHUMG00000015572
OMIM ID	173335
String ID	9606.ENSP00000354238
Drugbank ID	BE0000457
PharmGKB ID	PA27791

Target gene [ENPP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012395	chr6	4	3		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ENPP1 expression and immune infiltrating cell level correlation result in HBV+ samples
ENPP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).