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HTLV1 Target gene Detail Information

> EML3 Gene Search Result


Gene Information
Gene Name EML3
Gene ID 256364
Gene Full Name echinoderm microtubule associated protein like 3
Gene Alias ELP95; EMAP3; EMAP95
Transcripts ENSG00000149499
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q32P44
HGNC ID HGNC:26666
VEGA ID OTTHUMG00000149817
OMIM ID 618118
String ID 9606.ENSP00000378254
PharmGKB ID PA142671910
Target gene [EML3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000098 chr11 2116 1677 985 4778 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of EML3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EML3 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of EML3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EML3 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of EML3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EML3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).