HIV Target gene Detail Information

> EML2 Gene Search Result

Gene Information

Gene Name	EML2
Gene ID	24139
Gene Full Name	echinoderm microtubule associated protein like 2
Gene Alias	ELP70; EMAP2; EMAP-2
Transcripts	ENSG00000125746
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O95834
HGNC ID	HGNC:18035
VEGA ID	OTTHUMG00000182127
OMIM ID	617494
String ID	9606.ENSP00000468312
PharmGKB ID	PA27768

Target gene [EML2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001151	chr19	201	4		205	View
4001230	chr19	187	4		191	View
4006641	chr19	22	1		23	View
4010722	chr19	6	2		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EML2 expression and immune infiltrating cell level correlation result in HIV+ samples
EML2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EML2 expression and immune infiltrating cell level correlation result in HIV+ samples
EML2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).