HTLV1 Target gene Detail Information

> ELOVL4 Gene Search Result

Gene Information

Gene Name	ELOVL4
Gene ID	6785
Gene Full Name	ELOVL fatty acid elongase 4
Gene Alias	ADMD; CT118; ISQMR; SCA34; STGD2; STGD3
Transcripts	ENSG00000118402
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID	Q9GZR5
HGNC ID	HGNC:14415
VEGA ID	OTTHUMG00000015087
OMIM ID	605512
String ID	9606.ENSP00000358831
Drugbank ID	BE0002247
PharmGKB ID	PA27763

Target gene [ELOVL4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6015563	chr6	13	1		14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of ELOVL4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ELOVL4 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of ELOVL4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ELOVL4 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ELOVL4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ELOVL4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).