HBV Target gene Detail Information

> ELN Gene Search Result

Gene Information

Gene Name	ELN
Gene ID	2006
Gene Full Name	elastin
Gene Alias	WS; WBS; SVAS; ADCL1
Transcripts	ENSG00000049540
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Predicted to be secreted;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID	P15502
HGNC ID	HGNC:3327
VEGA ID	OTTHUMG00000150229
OMIM ID	130160
String ID	9606.ENSP00000351807
Drugbank ID	BE0001046
PharmGKB ID	PA27757

Target gene [ELN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008515	chr7	12	6	2	20	View
1009163	chr7	11	6		17	View
1012593	chr7	6			6	View
1013621	chr7		5		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ELN expression and immune infiltrating cell level correlation result in HBV+ samples
ELN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).