HIV Target gene Detail Information

> ELK4 Gene Search Result


Gene Information
Gene Name ELK4
Gene ID 2005
Gene Full Name ELK4, ETS transcription factor
Gene Alias SAP1
Transcripts ENSG00000158711
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P28324
HGNC ID HGNC:3326
VEGA ID OTTHUMG00000037221
OMIM ID 600246
String ID 9606.ENSP00000350681
PharmGKB ID PA27753
Target gene [ELK4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000734 chr1 102 136 61 299 View
4015942 chr1 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of ELK4 expression and immune infiltrating cell level correlation result in HIV+ samples
ELK4 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of ELK4 expression and immune infiltrating cell level correlation result in HIV+ samples
ELK4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).