HIV Target gene Detail Information

> ELK4 Gene Search Result

Gene Information

Gene Name	ELK4
Gene ID	2005
Gene Full Name	ELK4, ETS transcription factor
Gene Alias	SAP1
Transcripts	ENSG00000158711
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	P28324
HGNC ID	HGNC:3326
VEGA ID	OTTHUMG00000037221
OMIM ID	600246
String ID	9606.ENSP00000350681
PharmGKB ID	PA27753

Target gene [ELK4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000734	chr1	102	136	61	299	View
4015942	chr1				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ELK4 expression and immune infiltrating cell level correlation result in HIV+ samples
ELK4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ELK4 expression and immune infiltrating cell level correlation result in HIV+ samples
ELK4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).