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HBV Target gene Detail Information

> ELK3 Gene Search Result


Gene Information
Gene Name ELK3
Gene ID 2004
Gene Full Name ELK3, ETS transcription factor
Gene Alias ERP; NET; SAP2; SAP-2
Transcripts ENSG00000111145
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Mitochondria;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function Oncogene
Uniport_ID P41970
HGNC ID HGNC:3325
VEGA ID OTTHUMG00000170364
OMIM ID 600247
String ID 9606.ENSP00000228741
PharmGKB ID PA27752
Target gene [ELK3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007422 chr12 10 6 11 27 View
1008932 chr12 16 2 18 View
1010290 chr12 13 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ELK3 expression and immune infiltrating cell level correlation result in HBV+ samples
ELK3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).