HIV Target gene Detail Information

> EIF4H Gene Search Result

Gene Information

Gene Name	EIF4H
Gene ID	7458
Gene Full Name	eukaryotic translation initiation factor 4H
Gene Alias	WSCR1; WBSCR1; eIF-4H
Transcripts	ENSG00000106682
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q15056
HGNC ID	HGNC:12741
VEGA ID	OTTHUMG00000023025
OMIM ID	603431
String ID	9606.ENSP00000265753
PharmGKB ID	PA162384997

Target gene [EIF4H] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002632	chr7	77	7	2	86	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EIF4H expression and immune infiltrating cell level correlation result in HIV+ samples
EIF4H expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EIF4H expression and immune infiltrating cell level correlation result in HIV+ samples
EIF4H expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).