HIV Target gene Detail Information

> EIF2S2 Gene Search Result

Gene Information

Gene Name	EIF2S2
Gene ID	8894
Gene Full Name	eukaryotic translation initiation factor 2 subunit beta
Gene Alias	EIF2; EIF2B; PPP1R67; EIF2beta; eIF-2-beta
Transcripts	ENSG00000125977
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Nucleoli;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P20042
HGNC ID	HGNC:3266
VEGA ID	OTTHUMG00000032287
OMIM ID	603908
String ID	9606.ENSP00000364119
PharmGKB ID	PA27696

Target gene [EIF2S2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007675	chr20	18			18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EIF2S2 expression and immune infiltrating cell level correlation result in HIV+ samples
EIF2S2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).