HIV Target gene Detail Information

> EIF2B4 Gene Search Result

Gene Information

Gene Name	EIF2B4
Gene ID	8890
Gene Full Name	eukaryotic translation initiation factor 2B subunit delta
Gene Alias	EIF2B; EIF-2B; EIF2Bdelta
Transcripts	ENSG00000115211
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear membrane;Actin filaments;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9UI10
HGNC ID	HGNC:3260
VEGA ID	OTTHUMG00000151927
OMIM ID	606687
String ID	9606.ENSP00000394869
PharmGKB ID	PA27691

Target gene [EIF2B4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4300052	chr2	13	1		14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EIF2B4 expression and immune infiltrating cell level correlation result in HIV+ samples
EIF2B4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EIF2B4 expression and immune infiltrating cell level correlation result in HIV+ samples
EIF2B4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).