HIV Target gene Detail Information

> EIF2A Gene Search Result

Gene Information

Gene Name	EIF2A
Gene ID	83939
Gene Full Name	eukaryotic translation initiation factor 2A
Gene Alias	CDA02; EIF-2A; MST089; MSTP004; MSTP089
Transcripts	ENSG00000144895
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Mitochondria;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9BY44
HGNC ID	HGNC:3254
VEGA ID	OTTHUMG00000159775
OMIM ID	609234
String ID	9606.ENSP00000417229
PharmGKB ID	PA143485453

Target gene [EIF2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003271	chr3	30	17	18	65	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EIF2A expression and immune infiltrating cell level correlation result in HIV+ samples
EIF2A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EIF2A expression and immune infiltrating cell level correlation result in HIV+ samples
EIF2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).