HIV Target gene Detail Information

> EHMT1 Gene Search Result

Gene Information

Gene Name	EHMT1
Gene ID	79813
Gene Full Name	euchromatic histone lysine methyltransferase 1
Gene Alias	GLP; GLP1; KMT1D; KLEFS1; FP13812; EHMT1-IT1; EUHMTASE1; Eu-HMTase1
Transcripts	ENSG00000181090
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9H9B1
HGNC ID	HGNC:24650
VEGA ID	OTTHUMG00000020995
OMIM ID	607001
String ID	9606.ENSP00000417980
PharmGKB ID	PA134941393

Target gene [EHMT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000908	chr9	248	3		251	View
4000921	chr9	87	90	72	249	View
4002659	chr9	81	4		85	View
4003474	chr9	60			60	View
4004473	chr9	34	4	5	43	View
4004733	chr9	33	2	5	40	View
4007882	chr9	15	1	1	17	View
4009635	chr9	11			11	View
4010079	chr9	8	2		10	View
4011008	chr9	6	1		7	View
4013232	chr9	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EHMT1 expression and immune infiltrating cell level correlation result in HIV+ samples
EHMT1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EHMT1 expression and immune infiltrating cell level correlation result in HIV+ samples
EHMT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).