HIV Target gene Detail Information

> EHD4 Gene Search Result


Gene Information
Gene Name EHD4
Gene ID 30844
Gene Full Name EH domain containing 4
Gene Alias PAST4
Transcripts ENSG00000103966
Virus HIV
Gene Type protein coding
HPA Location Info Plasma membrane;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9H223
HGNC ID HGNC:3245
VEGA ID OTTHUMG00000130370
OMIM ID 605892
String ID 9606.ENSP00000220325
PharmGKB ID PA27680
Target gene [EHD4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000066 chr15 81 963 364 1408 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of EHD4 expression and immune infiltrating cell level correlation result in HIV+ samples
EHD4 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of EHD4 expression and immune infiltrating cell level correlation result in HIV+ samples
EHD4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).