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HBV Target gene Detail Information

> EGFR Gene Search Result


Gene Information
Gene Name EGFR
Gene ID 1956
Gene Full Name epidermal growth factor receptor
Gene Alias ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
Transcripts ENSG00000146648
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Plasma membrane;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins
Gene Function Oncogene
Uniport_ID P00533
HGNC ID HGNC:3236
VEGA ID OTTHUMG00000023661
OMIM ID 131550
String ID 9606.ENSP00000275493
Drugbank ID BE0000767
Drug (Cytoscape Annotation) Gefitinib;Erlotinib Hydrochloride;Dasatinib;AfatinibDimaleate;Lapatinib Ditosylate;Vandetanib;Docetaxel;Panitumumab;Cetuximab;Imatinib Mesylate;Ibrutinib;Sunitinib Malate;Bosutinib;Necitumumab
PharmGKB ID PA7360
FDA Approved Drug Afatinib;Panitumumab;Erlotinib;Gefitinib;Dacomitinib;Cetuximab;Necitumumab;Osimertinib;Vandetanib;Lapatinib;Atezolizumab;Ipilimumab;Nivolumab;Pembrolizumab;Ramucirumab
Target gene [EGFR] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 31731368 A181T
RT
D
C
 View

Target gene [EGFR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010892 chr7 9 1 10 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).