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HBV Target gene Detail Information

> EFTUD2 Gene Search Result


Gene Information
Gene Name EFTUD2
Gene ID 9343
Gene Full Name elongation factor Tu GTP binding domain containing 2
Gene Alias MFDM; MFDGA; Snu114; Snrp116; SNRNP116; U5-116KD
Transcripts ENSG00000108883
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;Vesicles;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q15029
HGNC ID HGNC:30858
VEGA ID OTTHUMG00000179865
OMIM ID 603892
String ID 9606.ENSP00000392094
PharmGKB ID PA142671915
Target gene [EFTUD2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007314 chr17 13 15 28 View
1007556 chr17 12 14 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of EFTUD2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
EFTUD2 expression: Low -> High
Lollipop of EFTUD2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of EFTUD2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EFTUD2 expression and immune infiltrating cell level correlation result in HBV+ samples
EFTUD2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).