HPV Target gene Detail Information

> EFR3B Gene Search Result

Gene Information

Gene Name	EFR3B
Gene ID	22979
Gene Full Name	EFR3 homolog B
Gene Alias	KIAA0953
Transcripts	ENSG00000084710
Virus	HPV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Actin filaments;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9Y2G0
HGNC ID	HGNC:29155
VEGA ID	OTTHUMG00000151988
OMIM ID	616797
String ID	9606.ENSP00000384081
PharmGKB ID	PA162384473

Target gene [EFR3B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5400180	chr2	21	1	1	23	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE40774 (GEO)	Head and neck squamous cell carcinoma	134	Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774
HeatMap of cell type fractions in all samples	Lollipop of EFR3B expression and immune infiltrating cell level correlation result in HPV+ samples
EFR3B expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of EFR3B expression and immune infiltrating cell level correlation result in HPV+ samples
EFR3B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).