HBV Target gene Detail Information

> EFR3A Gene Search Result


Gene Information
Gene Name EFR3A
Gene ID 23167
Gene Full Name EFR3 homolog A
Transcripts ENSG00000132294
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q14156
HGNC ID HGNC:28970
VEGA ID OTTHUMG00000150552
OMIM ID 611798
String ID 9606.ENSP00000254624
PharmGKB ID PA162384422
Target gene [EFR3A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004433 chr8 15 27 39 81 View
1401252 chr8 15 27 39 81 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EFR3A expression and immune infiltrating cell level correlation result in HBV+ samples
EFR3A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).