HTLV1 Target gene Detail Information

> EFCAB6 Gene Search Result

Gene Information

Gene Name	EFCAB6
Gene ID	64800
Gene Full Name	EF-hand calcium binding domain 6
Gene Alias	DJBP; HSCBCIP1; dJ185D5.1
Transcripts	ENSG00000186976
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5THR3
HGNC ID	HGNC:24204
VEGA ID	OTTHUMG00000150522
String ID	9606.ENSP00000262726
PharmGKB ID	PA162384324

Target gene [EFCAB6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005594	chr22	47	5	32	84	View
6007757	chr22	34	12	6	52	View
6009751	chr22	35			35	View
6016929	chr22	9	1	1	11	View
6028953	chr22		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of EFCAB6 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EFCAB6 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of EFCAB6 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EFCAB6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).