HIV Target gene Detail Information

> EEFSEC Gene Search Result


Gene Information
Gene Name EEFSEC
Gene ID 60678
Gene Full Name eukaryotic elongation factor, selenocysteine-tRNA specific
Gene Alias SELB; EFSEC
Transcripts ENSG00000284869
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID P57772
HGNC ID HGNC:24614
VEGA ID OTTHUMG00000159659
OMIM ID 607695
String ID 9606.ENSP00000254730
PharmGKB ID PA142671916
Target gene [EEFSEC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004807 chr3 36 3 39 View
4008354 chr3 14 1 15 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of EEFSEC expression and immune infiltrating cell level correlation result in HIV+ samples
EEFSEC expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).