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HBV Target gene Detail Information

> EEF2K Gene Search Result


Gene Information
Gene Name EEF2K
Gene ID 29904
Gene Full Name eukaryotic elongation factor 2 kinase
Gene Alias eEF-2K; CaMKIII; HSU93850
Transcripts ENSG00000284161
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID O00418
HGNC ID HGNC:24615
VEGA ID OTTHUMG00000094771
OMIM ID 606968
String ID 9606.ENSP00000263026
PharmGKB ID PA134992891
Target gene [EEF2K] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006145 chr16 32 10 42 View
1401657 chr16 32 10 42 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of EEF2K expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
EEF2K expression: Low -> High
Lollipop of EEF2K expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of EEF2K expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EEF2K expression and immune infiltrating cell level correlation result in HBV+ samples
EEF2K expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).