HTLV1 Target gene Detail Information

> EEF1A1 Gene Search Result

Gene Information

Gene Name	EEF1A1
Gene ID	1915
Gene Full Name	eukaryotic translation elongation factor 1 alpha 1
Gene Alias	CCS3; EF1A; PTI1; CCS-3; EE1A1; EEF-1; EEF1A; EF-Tu; LENG7; eEF1A-1; GRAF-1EF; HNGC:16303
Transcripts	ENSG00000156508
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene & Oncogene
Uniport_ID	P68104
HGNC ID	HGNC:3189
VEGA ID	OTTHUMG00000015031
OMIM ID	130590
String ID	9606.ENSP00000339063
Drugbank ID	BE0004528
PharmGKB ID	PA27625

Target gene [EEF1A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003609	chr6	149	1		150	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of EEF1A1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EEF1A1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of EEF1A1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EEF1A1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of EEF1A1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
EEF1A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).