HIV Target gene Detail Information

> EED Gene Search Result

Gene Information

Gene Name	EED
Gene ID	8726
Gene Full Name	embryonic ectoderm development
Gene Alias	HEED; COGIS; WAIT1
Transcripts	ENSG00000074266
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O75530
HGNC ID	HGNC:3188
VEGA ID	OTTHUMG00000167209
OMIM ID	605984
String ID	9606.ENSP00000263360
PharmGKB ID	PA27624

Target gene [EED] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004479	chr11	40	3		43	View
4007019	chr11	4	17		21	View
4012695	chr11	3	1		4	View
4014340	chr11	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EED expression and immune infiltrating cell level correlation result in HIV+ samples
EED expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EED expression and immune infiltrating cell level correlation result in HIV+ samples
EED expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).