HBV Target gene Detail Information

> EEA1 Gene Search Result


Gene Information
Gene Name EEA1
Gene ID 8411
Gene Full Name early endosome antigen 1
Gene Alias MST105; ZFYVE2; MSTP105
Transcripts ENSG00000102189
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q15075
HGNC ID HGNC:3185
VEGA ID OTTHUMG00000170110
OMIM ID 605070
String ID 9606.ENSP00000317955
Drugbank ID BE0001815
PharmGKB ID PA27621
Target gene [EEA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009374 chr12 16 16 View
1017325 chr12 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EEA1 expression and immune infiltrating cell level correlation result in HBV+ samples
EEA1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).