HIV Target gene Detail Information

> EDRF1 Gene Search Result


Gene Information
Gene Name EDRF1
Gene ID 26098
Gene Full Name erythroid differentiation regulatory factor 1
Gene Alias C10orf137
Transcripts ENSG00000107938
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Centrosome;Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q3B7T1
HGNC ID HGNC:24640
VEGA ID OTTHUMG00000019233
String ID 9606.ENSP00000349244
PharmGKB ID PA134873666
Target gene [EDRF1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001275 chr10 14 157 13 184 View
4008912 chr10 3 9 1 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of EDRF1 expression and immune infiltrating cell level correlation result in HIV+ samples
EDRF1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).