HBV Target gene Detail Information

> EDEM3 Gene Search Result

Gene Information

Gene Name	EDEM3
Gene ID	80267
Gene Full Name	ER degradation enhancing alpha-mannosidase like protein 3
Gene Alias	C1orf22
Transcripts	ENSG00000116406
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9BZQ6
HGNC ID	HGNC:16787
VEGA ID	OTTHUMG00000035387
OMIM ID	610214
String ID	9606.ENSP00000318147
PharmGKB ID	PA38186

Target gene [EDEM3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008314	chr1	21			21	View
1008315	chr1	21			21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of EDEM3 expression and immune infiltrating cell level correlation result in HBV+ samples
EDEM3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).