HBV Target gene Detail Information

> EDEM1 Gene Search Result

Gene Information

Gene Name	EDEM1
Gene ID	9695
Gene Full Name	ER degradation enhancing alpha-mannosidase like protein 1
Gene Alias	EDEM
Transcripts	ENSG00000134109
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Aggresome;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q92611
HGNC ID	HGNC:18967
VEGA ID	OTTHUMG00000154896
OMIM ID	607673
String ID	9606.ENSP00000256497
PharmGKB ID	PA128394554

Target gene [EDEM1] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	24282423	N123S	PreS2		View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of EDEM1 expression and immune infiltrating cell level correlation result in HBV+ samples
EDEM1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: LIHC