HIV Target gene Detail Information

> EDC3 Gene Search Result

Gene Information

Gene Name	EDC3
Gene ID	80153
Gene Full Name	enhancer of mRNA decapping 3
Gene Alias	YJDC; LSM16; MRT50; YJEFN2; hYjeF_N2-15q23
Transcripts	ENSG00000179151
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytoplasmic bodies;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q96F86
HGNC ID	HGNC:26114
VEGA ID	OTTHUMG00000142815
OMIM ID	609842
String ID	9606.ENSP00000320503
PharmGKB ID	PA142670551

Target gene [EDC3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003309	chr15	19	22	23	64	View
4004232	chr15	45	2		47	View
4012457	chr15	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EDC3 expression and immune infiltrating cell level correlation result in HIV+ samples
EDC3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).