HIV Target gene Detail Information

> EDAR Gene Search Result

Gene Information

Gene Name	EDAR
Gene ID	10913
Gene Full Name	ectodysplasin A receptor
Gene Alias	DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; ECTD10A; ECTD10B; EDA-A1R
Transcripts	ENSG00000135960
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted membrane proteins
Uniport_ID	Q9UNE0
HGNC ID	HGNC:2895
VEGA ID	OTTHUMG00000130982
OMIM ID	604095
String ID	9606.ENSP00000258443
PharmGKB ID	PA27602

Target gene [EDAR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002184	chr2	90	16		106	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EDAR expression and immune infiltrating cell level correlation result in HIV+ samples
EDAR expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EDAR expression and immune infiltrating cell level correlation result in HIV+ samples
EDAR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).