HTLV1 Target gene Detail Information

> EDA Gene Search Result

Gene Information

Gene Name	EDA
Gene ID	1896
Gene Full Name	ectodysplasin A
Gene Alias	ED1; HED; EDA1; EDA2; HED1; ODT1; XHED; ECTD1; XLHED; ED1-A1; ED1-A2; EDA-A1; EDA-A2; TNLG7C; STHAGX1
Transcripts	ENSG00000158813
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Vesicles;Lipid droplets;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q92838
HGNC ID	HGNC:3157
VEGA ID	OTTHUMG00000021764
OMIM ID	300451
String ID	9606.ENSP00000363680
PharmGKB ID	PA27601

Target gene [EDA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004964	chrX	85	12	3	100	View
6017267	chrX	11			11	View
6024592	chrX	3			3	View
6028978	chrX		1		1	View
6031928	chrX				0	View
6033296	chrX				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of EDA expression and immune infiltrating cell level correlation result in HTLV1+ samples
EDA expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of EDA expression and immune infiltrating cell level correlation result in HTLV1+ samples
EDA expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of EDA expression and immune infiltrating cell level correlation result in HTLV1+ samples
EDA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).