HTLV1 Target gene Detail Information

> ECT2L Gene Search Result


Gene Information
Gene Name ECT2L
Gene ID 345930
Gene Full Name epithelial cell transforming 2 like
Gene Alias LFDH; FBXO49; C6orf91; ARHGEF32; dJ509I19.2; dJ509I19.3; dJ509I19.5
Transcripts ENSG00000203734
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q008S8
HGNC ID HGNC:21118
VEGA ID OTTHUMG00000015679
String ID 9606.ENSP00000442307
PharmGKB ID PA134893289
Target gene [ECT2L] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6011443 chr6 16 6 4 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of ECT2L expression and immune infiltrating cell level correlation result in HTLV1+ samples
ECT2L expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).