HTLV1 Target gene Detail Information

> ECRG4 Gene Search Result


Gene Information
Gene Name ECRG4
Gene ID 84417
Gene Alias C2orf40
Transcripts ENSG00000119147
Virus HTLV1
Gene Type protein coding
HPA Location Info
Gene Function Suppressor gene
HGNC ID HGNC:24642
OMIM ID 611752
PharmGKB ID PA147358728
Target gene [ECRG4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000951 chr2 445 51 192 688 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of ECRG4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ECRG4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).