HTLV1 Target gene Detail Information

> ECRG4 Gene Search Result

Gene Information

Gene Name	ECRG4
Gene ID	84417
Gene Alias	C2orf40
Transcripts	ENSG00000119147
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Gene Function	Suppressor gene
HGNC ID	HGNC:24642
OMIM ID	611752
PharmGKB ID	PA147358728

Target gene [ECRG4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000951	chr2	445	51	192	688	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of ECRG4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
ECRG4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).