MCV Target gene Detail Information

> ECH1 Gene Search Result

Gene Information

Gene Name	ECH1
Gene ID	1891
Gene Full Name	enoyl-CoA hydratase 1
Gene Alias	HPXEL
Transcripts	ENSG00000282853
Virus	MCV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q13011
HGNC ID	HGNC:3149
VEGA ID	OTTHUMG00000182609
OMIM ID	600696
String ID	9606.ENSP00000221418
PharmGKB ID	PA27596

Target gene [ECH1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
7000003	chr19	106	10		116	View
7000004	chr19	97	1		98	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50451-GPL571 (GEO)	Merkel cell carcinoma	50	Merkel cell carcinoma (MCV+)(16), Merkel cell carcinoma (MCV-)(7), Merkel cell carcinoma cell line (MCV+)(1), Merkel cell carcinoma cell line MCC13 (MCV-)(3), Merkel cell carcinoma cell line MCC26 (MCV-)(3), Merkel cell carcinoma cell line Mkl-1 (MCV+)(6), Merkel cell carcinoma cell lineUISO(MCV-)(7), Merkel cell carcinoma cell line WaGa (MCV+)(7)

> Dataset: GSE50451-GPL571
HeatMap of cell type fractions in all samples	Lollipop of ECH1 expression and immune infiltrating cell level correlation result in MCV+ samples
ECH1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).