HIV Target gene Detail Information

> ECE1 Gene Search Result

Gene Information

Gene Name	ECE1
Gene ID	1889
Gene Full Name	endothelin converting enzyme 1
Gene Alias	ECE
Transcripts	ENSG00000117298
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P42892
HGNC ID	HGNC:3146
VEGA ID	OTTHUMG00000002625
OMIM ID	600423
String ID	9606.ENSP00000364028
Drugbank ID	BE0003793
PharmGKB ID	PA27594

Target gene [ECE1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012173	chr1		3	2	5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ECE1 expression and immune infiltrating cell level correlation result in HIV+ samples
ECE1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).