HBV Target gene Detail Information

> EBF4 Gene Search Result

Gene Information

Gene Name	EBF4
Gene ID	57593
Gene Full Name	EBF family member 4
Gene Alias	COE4; O/E-4
Transcripts	ENSG00000088881
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9BQW3
HGNC ID	HGNC:29278
VEGA ID	OTTHUMG00000031709
OMIM ID	609935
String ID	9606.ENSP00000370022
PharmGKB ID	PA162384262

Target gene [EBF4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000489	chr20	1722	317	41	2080	View
1402902	chr20	1722	317	41	2080	View
1404340	chr20	318	113	141	572	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of EBF4 expression and immune infiltrating cell level correlation result in HBV+ samples
EBF4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).