HBV Target gene Detail Information

> EBF1 Gene Search Result


Gene Information
Gene Name EBF1
Gene ID 1879
Gene Full Name EBF transcription factor 1
Gene Alias EBF; COE1; OLF1; O/E-1
Transcripts ENSG00000164330
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q9UH73
HGNC ID HGNC:3126
VEGA ID OTTHUMG00000130304
OMIM ID 164343
String ID 9606.ENSP00000322898
PharmGKB ID PA162384225
Target gene [EBF1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005874 chr5 25 16 5 46 View
1401562 chr5 25 16 5 46 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EBF1 expression and immune infiltrating cell level correlation result in HBV+ samples
EBF1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).