HIV Target gene Detail Information

> E2F7 Gene Search Result

Gene Information

Gene Name	E2F7
Gene ID	144455
Gene Full Name	E2F transcription factor 7
Transcripts	ENSG00000165891
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q96AV8
HGNC ID	HGNC:23820
VEGA ID	OTTHUMG00000169969
OMIM ID	612046
String ID	9606.ENSP00000323246
PharmGKB ID	PA134894421

Target gene [E2F7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000436	chr12	360	26	78	464	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of E2F7 expression and immune infiltrating cell level correlation result in HIV+ samples
E2F7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of E2F7 expression and immune infiltrating cell level correlation result in HIV+ samples
E2F7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).