HBV Target gene Detail Information

> DYNC2H1 Gene Search Result


Gene Information
Gene Name DYNC2H1
Gene ID 79659
Gene Full Name dynein cytoplasmic 2 heavy chain 1
Gene Alias ATD3; DHC2; DHC1b; DNCH2; DYH1B; SRTD3; SRPS2B; hdhc11
Transcripts ENSG00000187240
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;Cytosol;Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q8NCM8
HGNC ID HGNC:2962
VEGA ID OTTHUMG00000165941
OMIM ID 603297
String ID 9606.ENSP00000381167
PharmGKB ID PA27433
Target gene [DYNC2H1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009190 chr11 15 2 17 View
1012322 chr11 6 1 7 View
1019124 chr11 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DYNC2H1 expression and immune infiltrating cell level correlation result in HBV+ samples
DYNC2H1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).