HIV Target gene Detail Information

> DYNC1LI2 Gene Search Result

Gene Information

Gene Name	DYNC1LI2
Gene ID	1783
Gene Full Name	dynein cytoplasmic 1 light intermediate chain 2
Gene Alias	LIC2; DNCLI2
Transcripts	ENSG00000135720
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centrosome;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O43237
HGNC ID	HGNC:2966
VEGA ID	OTTHUMG00000137523
OMIM ID	611406
String ID	9606.ENSP00000258198
PharmGKB ID	PA27438

Target gene [DYNC1LI2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002660	chr16	85			85	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DYNC1LI2 expression and immune infiltrating cell level correlation result in HIV+ samples
DYNC1LI2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DYNC1LI2 expression and immune infiltrating cell level correlation result in HIV+ samples
DYNC1LI2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).