HIV Target gene Detail Information

> DYNC1H1 Gene Search Result

Gene Information

Gene Name	DYNC1H1
Gene ID	1778
Gene Full Name	dynein cytoplasmic 1 heavy chain 1
Gene Alias	p22; DHC1; DNCL; DYHC; HL-3; CMT2O; DHC1a; DNCH1; DNECL; Dnchc1; SMALED1
Transcripts	ENSG00000197102
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centrosome;Cytosol;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q14204
HGNC ID	HGNC:2961
VEGA ID	OTTHUMG00000171644
OMIM ID	600112
String ID	9606.ENSP00000348965
PharmGKB ID	PA27432

Target gene [DYNC1H1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002866	chr14	76	1		77	View
4005266	chr14	34			34	View
4011569	chr14	4	2		6	View
4300073	chr14	9			9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DYNC1H1 expression and immune infiltrating cell level correlation result in HIV+ samples
DYNC1H1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DYNC1H1 expression and immune infiltrating cell level correlation result in HIV+ samples
DYNC1H1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).