HBV Target gene Detail Information

> DUX4 Gene Search Result

Gene Information

Gene Name	DUX4
Gene ID	100288687
Gene Full Name	double homeobox 4
Gene Alias	DUX4L
Transcripts	ENSG00000283949
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;Cytosol;Golgi apparatus;
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters
Uniport_ID	Q9UBX2
HGNC ID	HGNC:50800
VEGA ID	OTTHUMG00000175568
OMIM ID	606009
String ID	9606.ENSP00000458065
PharmGKB ID	PA166180605

Target gene [DUX4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1400236	chr18	188	197	103	488	View
1404563	chr10	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DUX4 expression and immune infiltrating cell level correlation result in HBV+ samples
DUX4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).